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Transfer RNA

Adaptor RNA that carries a specific amino acid to the ribosome during translation.

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Transfer RNA

Adaptor RNA that carries a specific amino acid to the ribosome during translation.

It is a small RNA molecule that acts as an adaptor in translation: it carries a specific amino acid to the ribosome and pairs it with the corresponding codon of the messenger RNA through its anticodon.

Each of the twenty amino acids has at least one specific transfer RNA, charged by its corresponding aminoacyl-tRNA synthetase; correct codon-anticodon pairing is the basis of the fidelity of the genetic code.

The video shows how a special transfer RNA, charged with formylmethionine, settles into the start site, and how, once translation is underway, successive transfer RNAs enter through the A site carrying an amino acid, occupy the P site while holding the growing chain, and finally leave the ribosome through the E site once their job is done.

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Sources · original ES transcript

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