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Shine-Dalgarno sequence

Sequence in bacterial messenger RNA that positions the ribosome at the start codon.

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Shine-Dalgarno sequence

Sequence in bacterial messenger RNA that positions the ribosome at the start codon.

It is a short sequence located in bacterial messenger RNA, upstream of the start codon, that pairs by complementarity with a region of the 16S ribosomal RNA.

It is specific to prokaryotes, and its correct recognition is essential for translation to begin exactly at the right codon, keeping the reading frame of the protein to be synthesized.

The video explains that the messenger RNA contains this sequence, which pairs with a complementary region of the 16S ribosomal RNA, and that this interaction allows the start codon to be correctly positioned.

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Sources · original ES transcript

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