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The Rule Behind All Life | The Central Dogma
How does the information stored in DNA become a protein? This video walks through the Central Dogma of Molecular Biology. It starts with Rosalind Franklin and Photo 51 to understand the structure of DNA and, from there, explores how genetic information is preserved and used:...
32 resources
- 1. Historia
- [EN] Cobb, M. (2017). 60 years ago, Francis Crick changed the logic of biology. PLOS Biology, 15(9), e2003243..pdf PDF
- [EN] Cobb, M., & Comfort, N. (2023). What Rosalind Franklin truly contributed to the discovery of DNA’s structure. Nature, 616(7958), 657–660. External link
- [EN] Crick, F. H. C. (1958). On protein synthesis. Symposia of the Society for Experimental Biology, 12, 138–163. External link
- [EN] NobelPrize.org. (1975). The Nobel Prize in Physiology or Medicine 1975. External link
- [EN] OpenStax. (2016). 10.1 Using microbiology to discover the secrets of life (en Microbiology).pdf PDF
- 2. ADN
- 3. Replicación
- [EN] Aequorea. (2026). DNA replication in Escherichia coli. [PDF document]. Retrieved from aequorea.net.pdf PDF
- [EN] Meselson, M., & Stahl, F. W. (1958). The replication of DNA in Escherichia coli. PNAS, 44(7), 671–682. External link
- [EN] OpenStax. (2016). 11.2 DNA replication (en Microbiology).pdf PDF
- [EN] Robinson, A., Causer, R. J., & Dixon, N. E. (2012). Architecture and conservation of the bacterial DNA replication machinery, an underexploited drug target. Current Drug Targets, 13(3), 352–372..pdf PDF
- [EN] Shamanna, R. A., et al. (2017). Recent advances in understanding Werner syndrome. F1000Research, 6, 1779..pdf PDF
- [EN] Vanden Broeck, A., et al. (2019). Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex. Nature Communications, 10, 4935..pdf PDF
- [ES] Aequorea. (2026). Replicación del ADN en Escherichia coli. [Documento PDF]. Recuperado de aequorea.net.pdf PDF
- 4. Transcripción
- [EN] Aequorea. (2026). Transcription in Escherichia coli. [PDF document]. Retrieved from aequorea.net.pdf PDF
- [EN] Bera, S. C., et al. (2022). Quantitative parameters of bacterial RNA polymerase open-complex formation, stabilization and disruption on a consensus promoter. Nucleic Acids Research, 50(13), 7511–7528..pdf PDF
- [EN] Coulombe, B., et al. (2021). POLR3-related leukodystrophy How do mutations affecting RNA polymerase III subunits cause hypomyelination. Faculty Reviews, 10, 12..pdf PDF
- [EN] OpenStax. (2016). 11.3 RNA transcription (en Microbiology).pdf PDF
- [EN] OpenStax. (2016). 11.7 Gene regulation Operon theory (en Microbiology).pdf PDF
- [EN] Song, E., et al. (2022). Rho-dependent transcription termination proceeds via three routes. Nature Communications, 13, 1663..pdf PDF
- [ES] Aequorea. (2026). Transcripción en Escherichia coli. [Documento PDF]. Recuperado de aequorea.net.pdf PDF
- 5. Traducción
- [EN] Aequorea. (2026). Translation in Escherichia coli. [PDF document]. Retrieved from aequorea.net.pdf PDF
- [EN] Da Costa, L., Narla, A., & Mohandas, N. (2018). An update on the pathogenesis and diagnosis of Diamond–Blackfan anemia. F1000Research, 7, 1350..pdf PDF
- [EN] Ganesh, R. B., & Maerkl, S. J. (2022). Biochemistry of aminoacyl tRNA synthetase and tRNAs and their engineering for cell-free and synthetic cell applications. Frontiers in Bioengineering and Biotechnology, 10, 918659..pdf PDF
- [EN] Nirenberg, M. W., & Matthaei, J. H. (1961). The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides. PNAS, 47(10), 1588–1602. External link
- [EN] OpenStax. (2016). 11.4 Protein synthesis (translation) (en Microbiology).pdf PDF
- [EN] Tamura, K. (2016). The genetic code Francis Crick’s legacy and beyond. Life, 6(3), 36..pdf PDF
- [ES] Aequorea. (2026). Traducción en Escherichia coli. [Documento PDF]. Recuperado de aequorea.net.pdf PDF
- 6. Entrevista
- [EN] Angeles-Morales, E. B., et al. (2012). Evaluation of morphological changes of Aeromonas caviae Sch3 biofilm formation under optimal conditions. Advances in Microbiology, 2(4), 552–560..pdf PDF
- [EN] Mishal, R., et al. (2025). RNA-seq analysis of wild-type and mutated TBPL1 gene in breast cancer cells lines through CRISPR-Cas9 approach reveals novel molecular signatures. Scientific Reports, 15, 37578..pdf PDF
- [EN] Soria-Herrera, R. J., et al. (2026). Microbiological quality of purified water from vending machines Occurrence, antimicrobial resistance, and biofilm formation of Pseudomonas aeruginosa. Environments, 13(4), 207..pdf PDF
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