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How Glycolysis Works: The Metabolic Pathway Essential to Life
Your body has been doing this since before you were born, and it may never have been explained to you clearly. Glycolysis is one of the oldest and most universal metabolic pathways in life. From bacteria to the cells in your body, every living organism relies on it. This video...
21 resources
- 1. Concept and History
- [DE] Embden, G., & Deuticke, H. J. (1933). Über die Bedeutung der Phosphoglycerinsäure für die Glykolyse im Muskel. Hoppe-Seyler’s Zeitschrift für physiologische Chemie. External link
- [EN] Baranowski, T. (1950). Jakub Karol Parnas (1884–1949) The discoverer of phosphorolysis. Science External link
- [EN] Kresge, N., Simoni, R. D., & Hill, R. L. (2005). Otto Fritz Meyerhof and the elucidation of the glycolytic pathway. Journal of Biological Chemistry, 280(4), e3. External link
- [EN] Meyerhof, O. (1923). Energy conversions in muscle [Nobel lecture]. NobelPrize.org External link
- [EN] Molenaar, D., van Berlo, R., de Ridder, D., & Teusink, B. (2009). Shifts in growth strategies reflect tradeoffs in cellular economics. Molecular Systems Biology, 5, 323..pdf PDF
- 2. Pathway Development
- [EN] Bar-Even, A., Flamholz, A., Noor, E., & Milo, R. (2012). Rethinking glycolysis On the biochemical logic of metabolic pathways. Nature Chemical Biology, 8(6), 509–517 External link
- [EN] Merck - Sigma-Aldrich. (n.d.). Glycolysis via the Embden–Meyerhof–Parnas Glycolytic Pathway [Technical article] External link
- [EN] OpenStax. (2018). 7.2 Glycolysis (en Biology 2e) External link
- [EN] Schurr, A., & Gozal, E. (2015). Glycolysis at 75 Is it time to tweak the first elucidated metabolic pathway in history Frontiers in Neuroscience, 9, 170..pdf PDF
- [EN] Sánchez-Pascuala, Et. al. (2017). Refactoring the Embden–Meyerhof–Parnas pathway as a whole of portable GlucoBricks for implantation of glycolytic modules... ACS Synthetic Biology External link
- [ES] Aequorea. (2025). Mapa detallado de la vía de la Glucólisis. Recuperado de aequorea.net.pdf PDF
- 3. Regulation Points
- [EN] Chaudhry, R., & Varacallo, M. (2023). Biochemistry, Glycolysis. In StatPearls External link
- [EN] Lynch, E. M., et al. (2024). Structural basis for allosteric regulation of human phosphofructokinase-1. Nature Communications, 15, 7323. External link
- [EN] Usenik, A., & Legiša, M. (2010). Evolution of allosteric citrate binding sites on 6-phosphofructo-1-kinase. PLOS ONE, 5(11), e15447..pdf PDF
- [ES] Aequorea. (2025). Mecanismos de regulación enzimática Hexoquinasa, PFK-1 y Piruvato Quinasa. [Documento PDF]. Recuperado de aequorea.net.pdf PDF
- 4. ATP
- [EN] Flamholz, A., Noor, E., Bar-Even, A., & Milo, R. (2013). Glycolytic strategy as a tradeoff between energy yield and protein cost. PNAS, 110(24), 10039–10044 External link
- [EN] Lipmann, F. (1941). Metabolic generation and utilization of phosphate bond energy. Advances in Enzymology, 1, 99–162 External link
- [EN] OpenStax. (2018). 6.4 ATP Adenosine Triphosphate (en Biology 2e) External link
- [EN] Park, J. O., et al. (2019). Near-equilibrium glycolysis supports metabolic homeostasis and energy yield. Nature Chemical Biology, 15, 1001–1008 External link
- [ES] Aequorea. (2025). Estructura química y analogía energética del ATPADP. [Documento PDF]. Recuperado de aequorea.net.pdf PDF
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